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Med Vet International Simparica Chewables For Dogs 5.6 To 11 Pounds, Purple Label (3 Dose X 10)
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Simparica (sarolaner) kills adult fleas, and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (Lone Star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs 6 months of age or older and weighing 2.8 pounds or greater. See package insert for complete product details.
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Cayman Chemical JG-2016, Purity: ≥98%, CAS: 2887480-87-5, 25 mg
A HAT1 inhibitor (IC50 = 14.8 µM); selective for HAT1 over KAT2A and p300/CBP-associated factor (PCAF), for which it has no activity, KAT5, KAT6B, and KAT7 (IC50s = >100, >100, and 84.82 µM, respectively), CBP, and p300 (IC50s = 90.41 and 74.25 µM, respectively); reduces acetylation of H4K5 and H4K12 in hTert-HME1 mammary epithelial cells at 20 µM; reduces the growth of HCC1806 and A549 cells (EC50s = 10.4 and 1.9 µM, respectively); reduces intratumoral H4K12 acetylation in an A549 mouse xenograft model in a dose-dependent manner; reduces tumor growth in an A549 mouse xenograft model at 50 and 100 mg/kg once every three days
